Immunohistochemical expression of MMP-14 and MMP-2, and MMP-2 activity during human ovarian follicular development
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چکیده
منابع مشابه
Immunohistochemical expression of MMP-14 and MMP-2, and MMP-2 activity during human ovarian follicular development
BACKGROUND The aim of this study was to investigate the presence of MMP-14 and MMP-2 during human ovarian follicular development using immunohistochemistry, and the activity of MMP-2 in follicular fluid using zymography. METHODS Ovarian tissue collected from the archives of the Department of Pathology was examined and medical records and histopathology were reviewed. Follicular fluids were co...
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BACKGROUND In cancer, various MMPs play a role in progression and metastasis and their overexpression generally indicates a poor prognosis. MMP-14 is the main activator of MMP-2 and both molecules play a role in normal ovarian follicular development. Earlier reports indicated a prognostic value for both MMP-14 and MMP-2 in ovarian cancer. This study was designed to determine the prognostic valu...
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Dilated cardiomyopathy (DCM) is accompanied by myocytes and connective tissue changes. Matrix metalloproteinases (MMPs) play important roles in cardiac remodeling. It seems that the gelatinases (MMP-2 and MMP-9) are effective enzymes in cardiomyopathy. Dilated cardiomyopathy was confirmed in 22 dogs (patient group) including 11 female and 11 male by clinical examination, auscultation, thoracic ...
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ژورنال
عنوان ژورنال: Reproductive Biology and Endocrinology
سال: 2014
ISSN: 1477-7827
DOI: 10.1186/1477-7827-12-12